Tyler WH Backman

Postition

Bioengineering Doctoral Candidate

Email

{first initial}{last name} at ucr

Education

PhD in Bioengineering (in progress), University of California Riverside
BS in Physics, Oregon State University

Research Interests

I am interested in computational drug discovery, mathematical modeling of biological feedback systems, and inference from weak and noisy data. I am currently developing computational tools to identify new small molecule drugs and drug targets for the treatment of human disease.

Publications

• bioassayR: Cross-Target Analysis of Small Molecule Bioactivity.
  Backman TW, Girke T.
  J Chem Inf Model. 2016 Jul 1.
• Cheminformatic analysis of high-throughput compound screens.
  Backman TW, Girke T.
  Methods Mol Biol. 2014;1056:145-57.
• fmcsR: mismatch tolerant maximum common substructure searching in R.
  Wang Y, Backman TW, Horan K, Girke T.
  Bioinformatics. 2013 Nov 1;29(21):2792-4.
• Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression.
  Zou Z, Saha TT, Roy S, Shin SW, Backman TW, Girke T, White KP, Raikhel AS.
  Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2173-81. doi: 10.1073/pnas.1305293110. Epub 2013 Apr 30.
• ChemMine tools: an online service for analyzing and clustering small molecules.
  Backman TW, Cao Y, Girke T.
  Nucleic Acids Res. 2011 Jul;39(Web Server issue):W486-91.
• Computational and analytical framework for small RNA profiling by high-throughput sequencing.
  Fahlgren N, Sullivan CM, Kasschau KD, Chapman EJ, Cumbie JS, Montgomery TA, Gilbert SD, Dasenko M, Backman TW, Givan SA, Carrington JC.
  RNA. 2009 May;15(5):992-1002.
• Update of ASRP: the Arabidopsis Small RNA Project database.
  Backman TW, Sullivan CM, Cumbie JS, Miller ZA, Chapman EJ, Fahlgren N, Givan SA, Carrington JC, Kasschau KD.
  Nucleic Acids Res. 2008 Jan;36(Database issue):D982-5.